Partnership making linked government administrative data available for research across all four UK nations.
Application required Free TRENAMsDB · The NAMs database · Free · Open data
Human data for NAMs research, instead of animal studies
40 human databases, biobanks, cohorts and registries that support new approach methodologies (NAMs): what each one holds, who can use it and how to apply.
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- National gateways and data access services 10
- Health record databases Primary care, hospital and insurance claims 9
- Biobanks and population cohorts 15
- Disease and procedure registries 7
- Drug safety, toxicology and human exposure 7
- Social and administrative data 7
- Clinical trial registries and results data Coming soon
- Human-based laboratory and computational data Human cell, tissue, omics, in vitro and in silico databases 2
- Directories, catalogues and data standards 3
All resources
- Social and administrative data · National gateways and data access services Not yet verified by a curator
Around 14,500 pregnancies in the Bristol area from 1991–92, following parents, children and now grandchildren; includes prenatal exposure data.
Application required Fee applies Samples GeneticBiobanks and population cohorts Not yet verified by a curatorBiB
Over 13,000 families recruited during pregnancy (2007–11), ethnically diverse, with environmental and health data.
Application required Varies Samples GeneticBiobanks and population cohorts Not yet verified by a curatorformerly General Practice Research Database · formerly GPRD
Anonymised GP records for millions of UK patients, linkable to hospital, cancer, mortality and deprivation data. A core resource for drug-safety (pharmacoepidemiology) studies.
Application required Fee appliesHealth record databases · Drug safety, toxicology and human exposure Not yet verified by a curatorPeople aged 50+ in England, interviewed every two years since 2002; health, biomarkers, social and economic data.
Registration Free Samples GeneticBiobanks and population cohorts · Social and administrative data Not yet verified by a curatorEuropean Prospective Investigation into Cancer
Around 25,000 adults in Norfolk followed since 1993 — diet, lifestyle and chronic disease.
Application required Varies Samples GeneticBiobanks and population cohorts Not yet verified by a curatorGS
Family-based cohort of around 24,000 people in Scotland with genetic, health and linked NHS data.
Application required Fee applies Samples GeneticBiobanks and population cohorts Not yet verified by a curatorGEL · 100,000 Genomes Project · National Genomic Research Library · NGRL
Whole genomes from the 100,000 Genomes Project and the NHS Genomic Medicine Service, linked to clinical data (rare disease and cancer).
Application required Varies TRE GeneticBiobanks and population cohorts · Human-based laboratory and computational data Not yet verified by a curatorHDR UK Gateway · HDR Gateway
Searchable catalogue of hundreds of UK health datasets (NHS, cohorts, biobanks, registries) with metadata and access details.
Open FreeNational gateways and data access services · Directories, catalogues and data standards Not yet verified by a curatorHSE
Occupational ill-health, exposure and incident data for Great Britain.
Open FreeDrug safety, toxicology and human exposure · Social and administrative data Not yet verified by a curatorNew national service, announced April 2025 by the UK Government with Wellcome (£500m government, £100m Wellcome). A single secure route to access and link NHS health and care data, plus consented cohort and biobank data. First elements rolling out during 2026.
Application required Varies TRE GeneticNational gateways and data access services Not yet verified by a curatorHBS
Anonymised health and social care data for Northern Ireland.
Application required Varies TRENational gateways and data access services · Health record databases Not yet verified by a curatorCMP · Intensive Care National Audit and Research Centre
Patients admitted to adult intensive care units.
Application required VariesDisease and procedure registries Not yet verified by a curatorIMRD-UK · formerly The Health Improvement Network · formerly THIN
Anonymised UK primary care records from Vision practices.
Commercial licence CommercialHealth record databases Not yet verified by a curatoriDAP · Interactive Drug Analysis Profiles
Reports of suspected adverse drug reactions and medical device incidents in people across the UK.
Open FreeDrug safety, toxicology and human exposure Not yet verified by a curatorMWS
Over 1 million UK women recruited 1996–2001 via breast screening; linked to NHS cancer, hospital and death records.
Application required Varies SamplesBiobanks and population cohorts Not yet verified by a curatorNational Cancer Registration and Analysis Service · NCRAS · NCARDRS
National cancer registry and the congenital anomalies and rare disease registers (NCARDRS) for England.
Application required Fee appliesHealth record databases · Disease and procedure registries Not yet verified by a curatorNJR
Joint replacement operations and implant outcomes across England, Wales, Northern Ireland, Isle of Man and Guernsey.
Application required VariesDisease and procedure registries Not yet verified by a curatorEnquiries about human poisoning cases from across the NHS; annual reports summarise exposures and trends.
Registration FreeDrug safety, toxicology and human exposure Not yet verified by a curatorRoute for requesting NHS England datasets (e.g. HES, Civil Registration deaths, linked data).
Application required Fee appliesNational gateways and data access services Not yet verified by a curator